Nutrition Myths

Glucose metabolism

About 20% of glucose gets metabolized in the liver, which is quite different to fructose metabolism which occurs mostly in the liver. The rest is distributed to most of the body cells for energy production and storage (e.g. in muscles as glycogen). (1, 2)

Part of the ingested glucose will end up in the liver cells, specifically in components where the energy is produced called mitochondria, where:

  • some of the glucose is converted to energy (ATP), essential for the cells to perform their day to day functions, and;
  • some will be released from the mitochondria as a substance called citrate.

The elevated insulin (as a result of increased blood glucose) stimulates the lipid forming enzymes in the liver.
Citrate released from mitochondria, with the help of these enzymes, gets converted to VLDL particles which are then released to the bloodstream. VLDLs are associated with heart disease and obesity.

Related Posts

Chestnuts are more similar to whole grains than to nuts The culinary characteristics and the nutritional value of chestnuts are quite different from other nuts. They resemble more to whole grains in their carbohydrate to fat ratio.
Are fruit juices healthy? There are 6 reasons why fruit juices are not healthy, contrary to what is believed. These negative effects outweigh the health benefits derived from the nutrients of fruit juices.
What are healthy carbs? Healthy carbohydrates can be defined as unrefined carbohydrates that have a low impact on blood sugar levels, are low in fructose and high in dietary fiber. The list of healthy carbohydrates includes whole vegetables, fr...
Toxic effects of fructose metabolism Fructose is mostly metabolized in the liver. The result of this process produces a high amount of harmful substances which lead to metabolic syndrome and related diseases.

Get updates

Receive regular updates on nutrition myths, facts and curiosities. All based on the latest scientific evidence.